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Category Archives: Science/Biology
The Human Ovary: Steroidogenesis & Ovulation
When we last considered the human ovary, we were discussing a bit of anatomy and a lot of folliculogenesis. We learned about the different steps and changes that ovarian follicles undergo as they develop or become atretic. With the information from that … Continue reading
Posted in Science/Biology
Tagged androgen, androstenedione, corpus luteum, estradiol, follicle, folliculogenesis, FSH, GnRH, hormones, LH, menstrual cycle, oocyte, ovary, ovulation, PCOS
9 Comments
The Human Ovary: Anatomy & Follicular Development
Time flies when you’re having fun. And commuting (which is not fun). Well, time flies like an arrow but fruit flies like a banana… (By the way, that doesn’t look like a fruit fly on the right. To me, it … Continue reading
The Spectra of Gender, Sexual Orientation and Biological Sex
In a previous post — the one about the Genetics Behind Sex Determination and Differentiation — one reader left a comment that induced me to remove a sentence. The reader took issue with my statement that human gonadal sex develops … Continue reading
When the Genetics of Gonadal Differentiation & Development Don’t Go According to Plan – Part 3 of Where Do Ovaries (and Testes) Come From?
In the previous post, we talked about the genes that drive sex differentiation of the bi-potential embryonic gonad. I only mentioned a relatively small number of genes, but they control the events at or near the beginning of the signaling … Continue reading
Posted in Science/Biology
Tagged DSD, genetics of sex determination, gonads, intersex, ovary, sex determination, sry, testis
6 Comments
The Genetics Behind Sex Determination and Differentiation – Part 2 of Where Do Ovaries (and Testes) Come From?
I began this series of posts as a background with the goal of discussing Polycystic Ovary Syndrome in trans men. I thought that in order to understand what happens when things go wrong in ovarian function, we first need to … Continue reading
Posted in Science/Biology
Tagged bipotential gonad, embryonic gonad, fgf9, foxl2, genetics of sex determination, ovary, pgd2, primordial germ cells, rspo1, sex determination, sex differentiation, sox9, sry, stra8, testis
23 Comments
Sex Determination and Differentiation – Where Do Ovaries (and Testes) Come From?
Well, it’s 2011. Know what that means? It means it’s time to get back to SCIENCE! (Yes, I know, that makes absolutely no sense, but let’s get back to science anyway, shall we?) Near the end of last year, I … Continue reading
Posted in Science/Biology
Tagged embryonic gonad, fetal gonad, ovary, sex development, sex differentiation, testis
7 Comments
Odor Perception is Affected by Sex Hormones Too, and Then There’s This Business About Pheromones
In our last scientific episode, we had cake and pork chops. Oh, and we also talked about the effects of transitioning on a person’s scent. But really, that post gave only half of the story. To explain what I mean, … Continue reading
Posted in Science/Biology
Tagged odor, olfactory, pheromones, scent, sense of smell, transgender, transition, vomeronasal organ
9 Comments
Why Transitioning with Testosterone Tends to Transform Transmen’s ScenT
A trans guy asked me once, “Can you write about why my scent has changed since I went on testosterone? My girlfriend wants to know.” Of course she does. I’d heard of this phenomenon before, enough to make me believe … Continue reading
Posted in Science/Biology
Tagged acne, axilla, dermal microflora, DHT, scent, sebaceous glands, skin, sweat glands, testosterone, transgender, transition, transsexual
13 Comments
Part 4 Male Gender Identity in an Individual With Complete Androgen Insensitivity Syndrome
What I learned during summer workation – (as opposed to vacation, which it wasn’t): 1. Some intersex people really don’t like it when trans people claim to be intersex because they’re trans. 2. Some trans people really don’t like it … Continue reading
Posted in Science/Biology
Tagged androgen insensivity syndrome, androgen receptor, CAH, CAIS, gender, intersex, morphogen gradients, PAIS, SF1, somatic mosaicism, transsexual
54 Comments
When a Hysterectomy is Only a Hysterectomy. Notes from the Philadelphia Trans Health Conference – Part 3.
I learned something at the Philadelphia Trans Health Conference that made me sit up and take notice. Well, it’s not that I didn’t sit up and take notice of anything else, but this particular tidbit is worth repeating. I don’t remember who it was – … Continue reading →